Reference Number: 500
This work reports the anti-pathogenic effect of a commercially available water-based probiotic suspension, Symprove™, against three commonly encountered infectious organisms; Escherichia coli, methicillin-resistant Staphylococcus aureus (MRSA) and Shigella sonnei. An isothermal calorimetric assay was used to the monitor growth of the species individually and in binary combinations, while colony plate counting was used to enumerate viable cell numbers. It was observed that all pathogenic species were faster growing than the probiotic bacteria in Symprove™ after inoculation into growth medium yet in all instances bacterial enumeration at the end of the experiments revealed a significant reduction in the pathogen population compared with the controls. A control population between 108 and 109 CFU/ml was obtained for E. coli and S. sonnei whilst approximately 106 CFU/ml was obtained for MRSA. Upon co-incubation for 48 h, no viable counts were obtained for E. coli; a 4-log reduction was obtained for S. sonnei whilst MRSA numbers were down to less than 10 cells/ml. The results show that Symprove™ has antipathogenic activity against E. coli, S. sonnei and MRSA.
Significance of this study to the Baker:
We successfully nourish ourselves with plenty of prebiotic fibres when we consume our sourdough bakes. It is the probiotic microbes that feed off these prebiotics and subsequently provide us with the bountiful health benefits. Should we want to boost the levels of certain probiotic species within our gut, we can buy supplements and one of them is Symprove. This study shows that Symprove can be a useful supplement to use in order to get rid of any nasty pathogenic organisms that tend to arise when an individual has a dysbiotic gut microbiome. Like all probiotics , eating them in synbiosis with prebiotic dietary fibres, such as sourdough bread, will allow them to be nourished and therefore nourish you more!