Reference Number: 211
It is debated whether a low total diversity of the gut microbiota in early childhood is more important than an altered prevalence of particular bacterial species for the increasing incidence of allergic disease. The advent of powerful, cultivation-free molecular methods makes it possible to characterize the total microbiome down to the genus level in large cohorts.
We sought to assess microbial diversity and characterize the dominant bacteria in stool during the first year of life in relation to atopic eczema development.
Low intestinal microbial diversity during the first month of life was associated with subsequent atopic eczema.
SIGNIFICANCE OF THIS STUDY
Low diversity in the gut microbiota at an early age has been linked with increased incidence of eczema in the first two years of life. This indicates a potential role of the gut microbes in helping protect against allergic disease.